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EFFECT OF “YOJYO HENSHIKO: A NEW CHINESE HERB PRESCRIPTION” ON SERUM ALT(GPT) AND AST(GOT) LEVELS IN PATIENTS WITH HEPATIC DISEASES
S. Sha (Institute of Health Care with Oriental Herb and Medicine, Tokyo, Japan) M. Harada (Harada Hospital, Saitama, Japan
) N. Yanaihara (Yanaihara Institute Inc., Shizuoka, Japan)
2000/6/2-7/
[Aim]
Aim of the present study is to examine the effect of “Yojyo Henshiko”, a new
Chinese herb prescription, on patients with liver diseases including HCV.
[Background]
In our previous study, the Chinese herb prescription “Yojyo Henshiko” has been
shown to be effective in lowering serum levels of ALT(GPT) and AST(GOT) in rats with
hepatic disease induced by D-glucosamine.
[Composition]
“Yojyo Henshiko” is composed of extracts of Panax-Pseudo Ginseng, Denshichi-Tochusei,
Polygonati rhizoma, Licorices root.
[Method]
The prescription (1gram) was given orally three times a day after meals to
patients (n=20) with various hepatic diseases including HCV under the control
of physicians.
[Results]
1) Serum levels of ALT(GPT) and AST(GOT) of the patients examined were markedly lowered
after treatment with “Yojyo Henshiko” for ten days. Present reductions (mean
values) of serum ALT(GPT) and AST(GOT) levels were 18% and 59%, respectively, when
compared with those of patients before treatment.
2) In the case of normal adult, little change of serum ALT(GPT) and AST(GOT) levels was
observed.
[Conclusion]
1) These results substantiate clearly the effect of “Yojyo Henshiko” in lowering
the enhanced serum levels of ALT(GPT) and AST(GOT) in the patients with hepatic diseases.
2) Any side effects were not observed during the treatment.
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